Retatrutide

Retatrutide, also identified by the developmental code LY3437943, is a synthetic peptide investigated in published research as an agonist at the GIP, GLP-1 and glucagon receptors. Prime Peptides supplies it as a lyophilized material strictly for in-vitro laboratory research.

Reference databases report a molecular weight of approximately 4,731 g/mol for Retatrutide. The Prime Peptides reference profile records 4,731.3 g/mol. This information is provided for compound identification and laboratory reference only.

Published receptor pharmacology describes semaglutide as a GLP-1 receptor agonist, tirzepatide as a dual GIP and GLP-1 receptor agonist, and Retatrutide as a triple GIP, GLP-1 and glucagon receptor agonist. This is a comparison of receptor profiles reported in the research literature, not a claim of clinical equivalence or suitability.

Every batch goes through three layers of quality control. Our manufacturer runs its own QC and has its production independently tested by Janoshik Analytical. Then Vanguard or Janoshik tests every batch we stock again, for identity, HPLC purity, net content and endotoxins before we approve it for sale.

Every approved batch has its lab report on the Test Results page.

We target 99%+ purity by HPLC. The actual purity of each batch is measured independently and published in its lab report, so you can check the result yourself.

Follow the product label and batch documentation. Current product guidance is to store the sealed lyophilized vial at −20°C, protected from light, and to avoid repeated freeze-thaw cycles. Prime Peptides release testing verifies the batch against its release criteria; it does not independently establish product shelf life.

Peer-reviewed research is indexed on PubMed under both “Retatrutide” and “LY3437943.” The Selected Literature section on this page links to the discovery work by Coskun et al. and published studies by Jastreboff et al., Rosenstock et al. and Sanyal et al.

Each vial carries a batch number linked to its matching lab report (COA). Scan the QR code on the vial or search the batch number on Test Results to see that batch’s record and the original lab documents.